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Stroke recovery (the primary outcome) was monitored by behavioural tests (see ESM Methods: Assessment of stroke recovery): (1) a grip strength test, starting at 3 days after tMCAO, and weekly for 4 weeks, and (2) a corridor test, performed at weeks 1 and 4 after tMCAO (Fig
large thiamine doses can cause severe allergic reactions
Standard patient history can be augmented using ethnographic foodlife questions
As a selective estrogen receptor modulator (SERM), tamoxifen modulates estrogen signaling by binding to the estrogen receptor (ER) in breast tissue, preventing estrogen-driven transcriptional activation of genes that promote tumor cell growth
Avoid submerging the injection site in pools or hot tubs for 24 hours to minimize infection risk from the small skin puncture
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