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Common Side Effects (Both Peptides) Mild injection site irritation (redness, minor swelling) Headache (typically early in treatment) Temporary flushing or warmth after injection Mild changes in appetite When Medical Evaluation Is Essential Peptide therapy should always be preceded by: Comprehensive symptom assessment Medical and medication history review Baseline laboratory testing (IGF-1, metabolic panel, hormonal markers) Evaluation for contraindications (active malignancies, certain pituitary conditions) Ongoing monitoring includes periodic IGF-1 testing, symptom tracking, and dosage adjustments based on clinical response

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For more on how peptides function at the molecular level, see our guide on how peptides work and the broader overview of what peptides are

10.1016/j.jid.2021.08.326 22 KhatifH.BazziH