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While side effects are similar (mainly gastrointestinal, such as nausea or diarrhea), some patients may find Tirzepatides dual mechanism offers improved tolerability

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Obesity 28 , 860869 (2020)

In conclusion, we found that ALC significantly reduced SREBP2 and HMGCR expression, leading to decreased de novo cholesterol synthesis, lower serum cholesterol levels in HCD-fed mice, and attenuated atherosclerotic progression

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