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5 Conclusion This systematic review and meta-analysis indicate that sublingual and oral vitamin B12 administration provide efficacy comparable to intramuscular injection in improving serum cobalamin levels and reducing hyperhomocysteinaemia
Subcutaneous sites include the abdomen and outer upper arms
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However, higher-quality studies are necessary to prove these links
Insufficient intrinsic factor production, common in older adults due to age-related absorption decline, can also lead to deficiency
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