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After 12 weeks treatment, the reductions in HbA1c from baseline were 0.96% with 1.8mg MAR709, 0.9% with 1mg tirzepatide and 1.7% with 5mg tirzepatide

Subgroup analyses showed significant between-study heterogeneity in studies conducted in all subgroups that were not probable sources of heterogeneity (Table 3)

Currently, there is only two classes of drugs approved for the treatment of AD: N-methyl D -aspartate (NMDA) antagonist (memantine), and cholinesterase inhibitors (tacrine, Donepezil, galantamine, rivastigmine)