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The redox state shifted towards oxidation in peroxisomes, organelles associated with the detoxification of ROS and H 2 O 2 from photorespiration, during 22 h of darkness, whereas in chloroplasts, which are organelles associated with glutathione synthesis, the redox state was specifically affected by short-term excess light (3 h at 600 mol m 2 s 1 ) (Bratt et al
For cisplatin therapy, the dose of reduced glutathione should not exceed 35 mg per mg of cisplatin to avoid affecting chemotherapy, or follow the physician's instructions
Several triggers can be contributing to this condition, like nutritional deficiencies, thyroid issues, or other factors
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