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Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome

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Parkman HP, Yates KP, Hasler WL et al

Moreover, NAD has a crucial role in glycolysis, the citric acid cycle, and oxidative phosphorylation, since it acts as a proton acceptor, generating NADH, its reduced form, which collaborates with mitochondrial proton gradient (14)