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GLP-1RAs exert their anti-obesity effects primarily by amplifying signaling within this gutbrain axis, delivering a sustained satiety signal that overrides endogenous regulatory constraints ( Physiological GLP-1 does not function as a classical circulating hormone

These receptors regulate pigmentation signaling pathways responsible for eumelanin synthesis

Niacinamide: strengthens the skins protective barrier, smooths texture, and gives the face a healthy, matte radiance