Proposed mechanisms include regulation of endothelial function, influence on blood vessel formation, modulation of inflammatory signaling, and effects on connective tissue-associated processes such as collagen organization
Whether CagriSema ultimately occupies a meaningful commercial position in the obesity market will depend substantially on how the FDA evaluates the REDEFINE evidence package and how payers and prescribers weigh a well-evidenced but second-ranked option against the existing approved standard.
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