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Prolonged overdose of B6 (150-200 mg/day) over weeks can cause severe sensory-nervous-system dysfunction and ataxia.37 With normal usage serious adverse effects are not reported for pyridoxine (vitamin B6), however, diarrhoea, emesis and rosacea-like dermatitis may be observed in some cases (38)

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The work supports the chronic-administration tolerability of 5-Amino-1MQ in mouse models of obesity-linked type 2 diabetes

These peptides are widely used in wellness settings and are generally considered well tolerated when prescribed appropriately and monitored by a medical team