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Since most ingested allulose is absorbed and excreted in urine, with only a fraction reaching the colon, the direct microbiome effects may be less significant than initially hypothesized

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Neuroprotection studies in ischemia models, ALS models, and other neurodegenerative contexts have examined IGF-1 and IGF-1 LR3 effects on neuronal survival

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Funding The National Key Research and Development Program (2018YFE0196600), the China Postdoctoral Science Foundation (2020M670131), and the Beijing Postdoctoral Research Foundation (2020-ZZ-045)