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Food and Drug Administration issued concerns over the use of unapproved versions of glucagon-like peptide-1 (GLP-1) receptor agonists used for weight loss

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In SURMOUNT-1, a study in 2,539 adults with obesity, or excess weight and weight-related medical problems not including diabetes, people taking Zepbound as an adjunct to diet and exercise experienced substantial weight loss compared with placebo at 72 weeks