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How MSCs May Influence Autism Biology In preclinical models, MSC therapy has been associated with: Reduced neuroinflammation Decreased microglial activation Increased production of neurotrophic factors Enhanced synaptic plasticity Improved neuronal survival In mouse models of autism, MSC treatment has been linked to improvements in social interaction and reductions in repetitive behaviors
In the research community, sustained or supraphysiologic IGF-1 exposure is associated with progressive abdominal distension (sometimes called 'GH gut') and concern for cardiac hypertrophy
This co-administration strategy is a major focus of clinical trials today, moving these peptides from alternative medicine into supportive medicine [7, 8]
This result contrasts with some previous studies on DSIPs neuroprotective effects that have reported reduction in infarct size in other models [1]
& Maloney, C
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