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The coexistence of these conditions reflects shared pathophysiologic mechanisms, including insulin resistance, inflammation, and endothelial dysfunction

When melanocytes (melanin-producing cells) become hyperactive, they create patches of darker skin that can be difficult to fade with topical treatments alone

Cardiovascular and Vascular Benefits: GLP-1s can reduce the risk of major cardiovascular events, such as nonfatal heart attacks, nonfatal strokes, and cardiovascular deatheven in patients without diabetes

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