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However, semaglutide can cause gastrointestinal side effects (nausea, reflux), and coffee is acidic and can also irritate the stomach or trigger acid reflux in some people

Same approximate time

It is one of the clearest examples of how expanding from a single-pathway GLP-1 agonist to a dual incretin agonist can change the metabolic profile under investigation

Taking your oral dose first thing in the morning before breakfast, then waiting 30+ minutes to eat, maximizes absorption and ensures you're not interfering with medication effectiveness